منابع مشابه
Genetic diversity of carbapenem-hydrolyzing metallo-beta-lactamases from Chryseobacterium (Flavobacterium) indologenes.
The class B carbapenem-hydrolyzing beta-lactamase IND-1 has been characterized for Chryseobacterium indologenes strain 001. With internal primers for the bla gene for IND-1 (bla(IND-1)) and an internal bla(IND-1) probe, PCR amplifications failed, while hybridization results were positive when DNA from another C. indologenes isolate, strain CIP101026, was used as a template. Thus, a bla(IND)-rel...
متن کاملPlasmid-mediated carbencillin hydrolyzing beta-lactamases of Proteus mirabilis.
Since ABRAHAM and CHAIN') reported the production of beta((l)-lactamase by Escherichia coli, penicillinases have been shown to play an important role in the resistance of organisms against (3lactam antibiotics2.3). In many cases, the 46lactamases of Gram-negative bacteria have been shown to be mediated by R plasmids'), in contrast to chromosomally encoded drug resistance'). 46-Lactamases of Pro...
متن کاملIdentification of extended-spectrum, AmpC, and carbapenem- hydrolyzing beta-lactamases in Escherichia coli and Klebsiella pneumoniae by disk tests.
Antibiotic disks with and without clavulanic acid, 3-aminophenylboronic acid, or EDTA were tested with a set of 55 Klebsiella pneumoniae and Escherichia coli strains producing well-characterized extended-spectrum, AmpC, or carbapenem-hydrolyzing beta-lactamases. A relatively simple scheme was devised for distinguishing beta-lactamase types in clinical isolates with or without intact outer membr...
متن کاملOXA-58 and IMP-4 carbapenem-hydrolyzing beta-lactamases in an Acinetobacter junii blood culture isolate from Australia.
Hospital-acquired infections with Acinetobacter spp. have been reported worldwide (13). Success of the organism is attributed to its ability for long-term survival in a hospital environment and its ability to rapidly acquire resistance to antimicrobials (2). Carbapenems have been the agents of choice for serious Acinetobacter sp. infections, but unfortunately the clinical utility of this class ...
متن کاملCarbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2.
We investigated a Klebsiella oxytoca isolate demonstrating resistance to imipenem, meropenem, extended-spectrum cephalosporins, and aztreonam. The MICs of both imipenem and meropenem were 32 microg/ml. The beta-lactamase activity against imipenem and meropenem was inhibited in the presence of clavulanic acid. Isoelectric focusing studies demonstrated five beta-lactamases with pIs of 8.2 (SHV-46...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1997
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.41.2.223